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Codeine need to be applied with caution in people with respiratory impairment, head injuries, enhanced intracranial pressure, and in aged or debilitated sufferers. It should not be Employed in small children underneath 12 several years of age or in children below eighteen decades of age right after tonsillectomy and/or adenoidectomy.

Codeine is an opioid pain reliever and cough suppressant. It belongs to a category of medication often called opioid analgesics and operates by changing the best way the Mind and anxious program reply to pain. As well as its use as a painkiller, Codeine is usually made use of to treat cough a result of the flu or a chilly.

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Prior to the administration of flumazenil, needed measures should be instituted to secure airway, air flow and intravenous access. Flumazenil is meant as an adjunct to, not as an alternative for, good management of benzodiazepine overdose. Individuals dealt with with flumazenil need to be monitored for resedation, respiratory despair and also other residual benzodiazepine results for an correct interval immediately after procedure. The prescriber ought to pay here attention to a chance of seizure in association with flumazenil therapy, particularly in very long-expression benzodiazepine users As well as in cyclic antidepressant overdose.

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